Orthodontics

ORTHODONTICS

Enamel Remineralization

Dentoclude™ F  contains Bioactive glass which promotes remineralization of the demineralized enamel. Demineralization of teeth occurs when an acidic by-product of plaque wears away the enamel of the teeth. When a tooth is subjected to tooth decay, the minerals such as calcium and phosphate in the tooth begin to wear away hence “demineralization” and make the enamel in the tooth porous, sometimes leading to cavities or other dental issues. The standard of care to treat early caries lesions like White Spot Lesions (WSLs), regular plaque removal and fluoride application. Recently, phosphopeptide-amorphous calcium phosphate (CPP-ACP) is also used as an alternate therapy.

Bioglass has been extensively studied regarding the remineralization of WSLs. Taha et al. evaluated the effectiveness of bioactive glasses in inducing remineralization compared to topical fluoride and CPP-ACP treatment. They concluded that bioactive glasses may enhance enamel remineralization more effectively and earlier.

Dentoclude™ F  is a calcium–sodium–fluorophosphate silicate glass that releases calcium and phosphate ions. These ions increase the pH and result in precipitation of calcium phosphate and mineralization into hydroxyapatite. Advantage of using Dentoclude™ F  over the standard of care is that the CPP-ACP or other calcium-based products provide an initial calcium burst, while bioactive glass in Dentoclude™ F  exhibits a continuous calcium release.

The undeniable enamel damage in orthodontics occurs during the removal of residual orthodontic adhesive after the treatment. Slow-speed tungsten carbide is commonly used for this purpose. QMAT3 is a novel bioactive glass. In one study, tungsten carbide bur, QMAT3-air-abrasion, and Bioglass 45S5-air-abrasion were examined in vitro to evaluate enamel damage during the processes of removing residual orthodontic adhesive. The results show that QMAT3 bioactive glass has minimal enamel damage in comparison with Bioglass 45S5 air abrasion and tungsten carbide bur. Therefore, QMAT3 seems to offer a conservative approach for orthodontic adhesive removal.
References:
Skallevold HE, Rokaya D, Khurshid Z, Zafar MS. Bioactive Glass Applications in Dentistry. Int J Mol Sci. 2019 Nov 27;20(23):5960. doi: 10.3390/ijms20235960. PMID: 31783484;
PMCID: PMC6928922.

Jafari, N., Habashi, M.S., Hashemi, A. et al. Application of bioactive glasses in various dental fields. Biomater Res 26, 31 (2022). https://doi.org/10.1186/s40824-022-00274-6

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